2000s Cannabis Strains: What Defined This Era

The 2000s were defined by extreme potency and the rise of the West Coast medical market. Bubba Kush brought coffee-and-chocolate indica depth. Gorilla Glue #4 became synonymous with resin production. The decade saw the transition from black market to dispensary culture.

This page profiles 53 2000s strains. Explore every 2000s cannabis strain from this era below, or jump straight to the most influential cultivars in the featured section.

Notable 2000s Strains

A selection of the most influential 2000s cannabis genetics — the strains that defined the period and shaped everything that followed.

Bubba Kush

Pre-98 Bubba Kush, Bubba
Hybrid Hybrid (Indica-dominant 80/20)
Kush Family

OG Kush × 1993 New Orleans Indica ('Bubba'). The undisputed benchmark of heavy nighttime indicas. Born from an accidental 1996 pollination in a Silver Lake crawl space, Bubba Kush is world-famous for its roasted coffee, dark cocoa, and tranquilizing body melt.

Purple Kush

PK, Purps
Hybrid Indica-dominant Hybrid
Kush Family

A pure indica powerhouse crossing Hindu Kush with Purple Afghani. Known for extreme resin production and deep purple coloration.

LA Confidential

LA Con, LAC
Hybrid Indica-dominant Hybrid
Kush Family

An indica-dominant cross of OG LA Affie and Afghani. One of the first strains to offer functional daytime indica effects without total sedation.

Pineapple Express

Pineapple, P Express
Hybrid Sativa-dominant Hybrid
Fruit & Candy

A sativa-dominant cross of Trainwreck and Hawaiian. Immortalized by the 2008 Seth Rogen film, it became one of pop culture's most famous strains.

Gorilla Glue #4

GG4, Original Glue
Hybrid Hybrid (Indica-dominant)

(Chem's Sister × Sour Dubb) × Chocolate Diesel. The legendary accidental powerhouse created by Joesy Whales and Lone Watty, famous for glue-like resin output, a historic 2014 Cannabis Cup double sweep, and a landmark trademark battle.

Bruce Banner

Bruce Banner #1, BB1
Hybrid Sativa-dominant Hybrid

A potent cross of OG Kush and Strawberry Diesel. Named for the Hulk alter-ego — the effects hit hard and turn you into a giant green monster of relaxation.

The Complete 2000s Cannabis Strains Archive

Every 2000s strain in the database (53 total), sorted below. Click any card for the full genetic breakdown, lineage, terpenes, and Amsterdam availability.

Alien Kush

Alien Kush, Alien
Hybrid Indica-dominant Hybrid

The mysterious clone-only OG-family strain that gives Alien crosses their name — heavy, pungent, and deeply relaxing.

Amazing Haze

Amazing Amnesia, Amazing Haze Seeds
Hybrid Hybrid (Sativa-dominant)

Amnesia Haze x Caramella. A sweet, honeyed sativa hybrid famous on Amsterdam menus, combining energetic haze with calming caramel sweetness.

Amnesia Cordobesa

Amnesia Haze Cordobesa, La Cordobesa
Hybrid Hybrid (Sativa-dominant) 🇪🇸 Spanish Grown

Amnesia Haze phenotype. The legendary Spanish clone-only Amnesia cut from Cordoba, famous for its intense metallic-citrus haze aroma and electric sativa high.

Amnesia

Amnesia, Amnesia Haze
Hybrid Sativa

The definitive Amsterdam Haze strain that took coffee shops by storm with intense cerebral effects and lemony terps.

Banana Kush

Banana Kush, Banana OG Kush
Hybrid Hybrid (Indica-dominant)

OG Kush crossed with Banana genetics. Banana Kush became a West Coast classic known for its sweet tropical banana aroma and deeply relaxing indica effects.

Big Buddha Cheese

Buddha Cheese, BBC
Hybrid Hybrid (Indica-dominant)

UK Cheese x Afghani. The definitive Cheese hybrid cup winner bred by Big Buddha Seeds, enhancing the classic Cheese skunk with sweet Afghan spices.

Blackberry Kush

Blackberry Kush, BBK
Hybrid Indica-dominant Hybrid

A sweet, earthy blackberry-flavoured indica from Blackberry and Afghani genetics with an instantly calming full-body high.

Blue Cheese

Blue Cheese, Cheese Blue
Hybrid Indica-dominant Hybrid

The definitive UK cheese cross: Blueberry x UK Cheese. Blue Cheese combines the sweet berry notes of Blueberry with the pungent, savory funk of Cheese to create one of the most distinctive and beloved indica hybrids in British cannabis culture.

Bruce Banner

Bruce Banner #1, BB1
Hybrid Sativa-dominant Hybrid

A potent cross of OG Kush and Strawberry Diesel. Named for the Hulk alter-ego — the effects hit hard and turn you into a giant green monster of relaxation.

Cannalope Haze

Cannalope Haze, Cantaloupe Haze
Hybrid Hybrid (Sativa-dominant 95/5)

Haze Brothers × Mexican Michoacán. Bred by Don & Aaron of DNA Genetics in Amsterdam, Cannalope Haze is famous for sweet ripe cantaloupe melon terpenes and a soaring functional high.

Cannatonic

Cannatonic, Cannatonic CBD
Hybrid Hybrid

A pioneering high-CBD strain that changed medical cannabis, bred by Reserva Privada in Spain.

Chernobyl

Chernobyl, TGA Chernobyl
Hybrid Hybrid (Sativa-dominant 70/30)

Blood Wreck × Jack the Ripper. Bred by the late legendary breeder Subcool of TGA Genetics, Chernobyl is famous for its lime-sherbet Slurpee aroma and soaring energetic high.

Chocolate Diesel

Chocolate Diesel, Choc Diesel
Hybrid Hybrid (Sativa-dominant 60/40)

Sour Diesel × Chocolate Thai. A vintage East Coast / Southeast Asian fusion combining dark roast mocha-chocolate undertones with blistering sour kerosene fuel.

Critical Bilbo

Critical Mass Bilbo, Bilbo Cut
Hybrid Hybrid (Indica-dominant) 🇪🇸 Spanish Grown

Afghani x Skunk #1. The legendary Spanish clone-only selection from Bilbao that defines the entire Spanish cannabis market with its intense sweet honey-citrus aroma.

Death Star

Death Star, Deathstar OG
Hybrid Hybrid (Indica-dominant 75/25)

Sensi Star × Sour Diesel. Bred in Ohio in the early 2000s by Team Death Star, this legendary Midwest powerhouse is famous for wall-piercing skunk-diesel funk and crushing potency.

Fire OG

Fire OG, Fire OG Kush
Hybrid Hybrid

An elite OG Kush phenotype selected for extreme potency and fuel-forward terps. Fire OG elevated the OG Kush legacy with higher THC, thicker resin coverage, and a sharper, more aggressive lemon-pine-fuel profile.

G13 Haze

G13 Haze Barney's, Barney's G13 Haze
Hybrid Hybrid (Sativa-dominant)

G13 x Haze. A legendary sativa-dominant cup winner bred by Barney's Farm, combining the heavy potency of G13 with the energetic cerebral buzz of Haze.

Ghost OG

Ghost OG, Ghost
Hybrid Hybrid

A refined, all-purpose OG Kush phenotype prized for its balanced, deeply relaxing high — a steady dispensary staple that keeps yielding iconic crosses.

God Bud

God Bud, God Bud Strain
Hybrid Indica-dominant Hybrid

A Canadian-bred indica combining Hawaiian, Purple Skunk, and Purple Afghan genetics. God Bud became one of Canada's most beloved strains, known for its grape candy flavor and heavy sedative effects.

God's Gift

God's Gift, Gods Gift
Hybrid Hybrid (Indica-dominant 80/20)

OG Kush × Granddaddy Purple. A mid-2000s California medical icon combining the grape-candy sweetness of GDP with the heavy lemon-fuel knockout of OG Kush.

Granddaddy Purple

GDP, Grand Daddy Purp
Hybrid Hybrid (Indica-dominant 70/30)

Purple Urkle × Big Bud. Created in 2003 by medical activist Ken Estes, Granddaddy Purple defined the 'purple weed' revolution, pairing royal violet bag appeal with candied grape soda terpenes and profound therapeutic pain relief.

Grape Ape

Grape Ape, Grape Ape Indica
Hybrid Indica-dominant Hybrid

A three-way cross of Mendocino Purps, Skunk #1, and Afghani. Grape Ape became a West Coast classic prized for its intense grape flavor and heavy indica effects.

Green Ribbon

Green Ribbon, The Ribbon
Hybrid Hybrid (50/50 Balanced)

Green Crack × Trainwreck / Afghani. A legendary California medical clone famous for sweet pine, sour lime, and as the maternal mother of Fruity Pebbles OG (FPOG).

Harlequin

Harlequin, Harlequin CBD
Hybrid Sativa

The strain that launched the modern CBD revolution. Harlequin delivers a consistent 5:1 CBD-to-THC ratio with mango, citrus, and tropical fruit terpenes — gentle, clear-headed, and entirely anxiety-free. Bred by Flo White at Abraxas Seeds, it became the genetic foundation for an entire generation of high-CBD cultivars.

Hell's OG

Hell's OG, Hell's Angel OG
Hybrid Hybrid (Indica-dominant 80/20)

OG Kush × Blackberry. Originating in Southern California biker culture in the late 1990s, Hell's OG is notorious for heavy leather, diesel fuel, and crushing narcotic pain relief.

Jack the Ripper

Jack the Ripper, JTR
Hybrid Sativa

Subcool's celebrated Jack Herer × Space Queen sativa with electric lemon-lime flavors and a razor-sharp, energetic high.

Jager

Jager, Jager OG
Hybrid Indica

A UK underground legend. Jager emerged from the British clandestine scene in the early 2000s as a phenotype selection from the fabled Hannibal Lecter line — a clone-only cultivar famed for its distinctive grape-anise aroma, heavy resin production, and unshakeable reliability in cold, damp British conditions. It remains a cult favorite among UK growers and a key parent in modern indica breeding.

King Louis

King Louis XIII, Louis XIII OG
Hybrid Hybrid (Indica-dominant) 🇺🇸 Cali Import

OG Kush phenotype. The legendary California clone-only OG Kush phenotype that entered California's Top 10 best-sellers list in 2025 with its intense pine-fuel aroma.

Kosher Kush

Kosher Kush, Kosher
Hybrid Indica-dominant Hybrid

DNA Genetics' flagship indica. Kosher Kush is a Jamaican x OG Kush x Hindu Kush cross that won back-to-back High Times Cannabis Cups and set the standard for premium indica breeding in the late 2000s.

LA Confidential

LA Con, LAC
Hybrid Indica-dominant Hybrid
Kush Family

An indica-dominant cross of OG LA Affie and Afghani. One of the first strains to offer functional daytime indica effects without total sedation.

Larry OG

Larry OG, Larry OG Kush
Hybrid Hybrid (Indica-dominant)

An OG Kush phenotype selected in San Francisco by a grower named Larry. Larry OG became one of the most respected OG Kush expressions and a key parent in modern breeding.

Lemon Haze

Lemon Haze, Lemon Haze Sativa
Hybrid Sativa-dominant Hybrid

A sativa-dominant haze phenotype selected for intense lemon citrus aroma. Lemon Haze became one of the most recognizable sativa strains worldwide, prized for its uplifting effects.

Lemon Skunk

Lemon Skunk, DNA Lemon Skunk
Hybrid Hybrid (50/50 Balanced)

Las Vegas Lemon Skunk × Dutch Skunk #1. Bred by DNA Genetics, Lemon Skunk won the 2008 Spannabis Cup and directly fathered the world-famous Lemon Tree and Super Lemon Haze.

Mango Haze

Mango Haze, Mr. Nice Mango Haze
Hybrid Hybrid (Sativa-dominant 70/30)

Northern Lights #5 × Haze × Skunk #1. Bred by legendary geneticist Shantibaba at Mr. Nice Seedbank, Mango Haze is the fruity sibling of Super Silver Haze, famed for tropical mango terpenes.

Mendo Montage

Mendo Montage, Mendo
Hybrid Indica

The unsung hero of the Mendo Breath dynasty. Mendo Montage is an old-school Mendocino County indica that has been hiding in plain sight since the early 2000s — a sweet, floral, deeply calming cultivar that formed half of one of the most celebrated modern hybrids: Mendo Breath. Its vanilla-berry aroma and heavy body relaxation represent the best of the Emerald Triangle's pre-legalization breeding culture.

MK Ultra

MK Ultra, MK-Ultra
Hybrid Hybrid (Indica-dominant 85/15)

G13 × OG Kush. Bred in Amsterdam by TH Seeds, MK Ultra won 1st Place Indica at the 2003 High Times Cannabis Cup for its hypnotic, narcotic full-body couchlock.

Moby Dick

Dinafem Moby Dick
Hybrid Hybrid (Sativa-dominant) 🇪🇸 Spanish Grown

Haze x White Widow. The iconic high-yield Spanish sativa staple bred by Dinafem, known for its extreme potency, massive yield, and pine-incense terpene profile.

Motorbreath

Motorbreath, Motörhead
Hybrid Hybrid

A potent Chemdawg × SFV OG cross with heav-hitting gas, fuel, and earth — one of the loudest strains on the West Coast.

Pineapple Express

Pineapple, P Express
Hybrid Sativa-dominant Hybrid
Fruit & Candy

A sativa-dominant cross of Trainwreck and Hawaiian. Immortalized by the 2008 Seth Rogen film, it became one of pop culture's most famous strains.

Pink Kush

Pink Kush, Pink Kush OG
Hybrid Hybrid (Indica-dominant)

An OG Kush phenotype selected in British Columbia. Pink Kush became Canada's most iconic cannabis strain, known for its pink-hued pistils and heavy, narcotic indica effects.

Purple Kush

PK, Purps
Hybrid Indica-dominant Hybrid
Kush Family

A pure indica powerhouse crossing Hindu Kush with Purple Afghani. Known for extreme resin production and deep purple coloration.

Sensi Star

Sensi Star, Sensi Star (Paradise)
Hybrid Indica

The multiple-Cup-winning heavy indica from Paradise Seeds — pungent, spicy, and one of Europe's most decorated cultivars.

SFV OG

SFV OG, SFV OG Kush
Hybrid Hybrid

The San Fernando Valley OG cut — a legendary OG Kush phenotype that distilled the OG experience into its purest form. SFV OG is OG Kush in its leanest, meanest expression: pine, lemon, fuel, and devastating potency.

Sour Tsunami

Sour Tsunami, Ringo's Sour Tsunami
Hybrid Hybrid (CBD-rich 1:1 / 2:1)

Sour Diesel × NYC Diesel × Ferrari × Lawrence OG. Bred in Southern Humboldt by medical pioneer Lawrence Ringo, Sour Tsunami was the first strain in modern history bred specifically for high CBD.

Strawberry Diesel

Strawberry Diesel, Straw Diesel
Hybrid Hybrid (50/50 Balanced)

NYC Diesel × Strawberry Cough. Bred by Reservoir Seeds and Holy Smoke, Strawberry Diesel combines sweet candied strawberries with sharp sour kerosene fuel.

Strawberry Fields

Strawberry Fields, Strawberry Fields Kush
Hybrid Hybrid (Indica-dominant 65/35)

Strawberry Cough × Unknown Indica. An Upstate New York / Indiana legend prized for sweet ripe summer strawberries and tranquil, happy body relaxation.

Strawberry Haze

Arjan's Strawberry Haze, Strawberry Haze GHS
Hybrid Hybrid (Sativa-dominant)

Swiss Sativa x Northern Lights #5 x Haze. A highly popular Amsterdam sativa hybrid bred by Green House Seed Co, known for its sweet strawberry aroma and energetic, creative high.

Sugar Haze

Sugar Haze, Sweet Sugar Haze
Hybrid Hybrid (Sativa-dominant 80/20)

Santa Marta Colombian Gold × Original Haze. A sweet, highland South American sativa hybrid combining long-lasting psychedelic lucidity with sweet candied mint terpenes.

Super Lemon Haze

Super Lemon Haze, SLH
Hybrid Sativa-dominant Hybrid
Haze Family

Back-to-back Cannabis Cup winner 2008 and 2009. Lemon Skunk crossed with Super Silver Haze. The strain that made lemon terps mainstream and defined citrus-forward Haze hybrids for a generation.

Tahoe OG

Tahoe OG Kush, Tahoe OG
Hybrid Hybrid (Indica-dominant)

An OG Kush phenotype selected in the Lake Tahoe region. Tahoe OG is a high-elevation OG Kush selection known for extreme resin production, pine-fuel aroma, and heavy-handed effects.

The White

The White, Triangle White
Hybrid Indica

A mysterious, resin-soaked indica known for its complete white-out trichome coverage and subtle, mood-elevating effects.

Tres Dawg

Tres Dawg, Tres Stardawg
Hybrid Hybrid (Indica-dominant 60/40)

Chem D × Double Dawg. Bred in New York by JJ NYC of Top Dawg Seeds, Tres Dawg is the foundational breeding stud that fathered Stardawg, Guava, and the modern Dawg empire.

Wappa

Wappa, Paradise Wappa
Hybrid Hybrid (Indica-dominant 60/40)

Skunk selection × Sweet Indica. Bred in Amsterdam by Paradise Seeds, Wappa won multiple European cannabis cups for its sweet candied strawberry-cherry aroma and functional body stone.

2000s Cannabis Strains FAQ

What are the best 2000s weed strains?

The best 2000s weed strains are Gorilla Glue #4 (the late-2000s resin benchmark), Bubba Kush (coffee-chocolate indica depth), Bruce Banner (extreme THC sativa power), and Pineapple Express (the strain the 2008 film made a household name). Every one is profiled with lineage, THC, and effects in the 2000s archive below.

What were the strongest 2000s weed strains?

The 2000s were defined by extreme potency and the rise of the West Coast medical market. Gorilla Glue #4 set the benchmark for resin production, Bubba Kush brought coffee-and-chocolate indica depth, and the decade saw the transition from black-market to dispensary cannabis culture.

Is Gorilla Glue #4 a 2000s strain?

Yes. Gorilla Glue #4 (GG4) — Chem's Sister x Sour Dubb x Chocolate Diesel — emerged in the late 2000s/early 2010s and became synonymous with extreme resin production and potency, winning multiple Cannabis Cup awards.